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Controllability analysis of second-ordermulti-agent systemswith directed andweighted interconnection

Di GUO,Rong-hao ZHENG,Zhi-yun LIN,Gang-feng YAN

《信息与电子工程前沿（英文）》 2015年 第16卷 第10期   页码 838-847 doi: 10.1631/FITEE.1500069

摘要： This article investigates the controllability problem of multi-agent systems. Each agent is assumed to be governed by a second-order consensus control law corresponding to a directed and weighted graph. Two types of topology are considered. The first is concerned with directed trees, which represent the class of topology with minimum information exchange among all controllable topologies. A very simple necessary and sufficient condition regarding the weighting scheme is obtained for the controllability of double integrator multi-agent systems in this scenario. The second is concerned with a more general graph that can be reduced to a directed tree by contracting a cluster of nodes to a component. A similar necessary and sufficient condition is derived. Finally, several illustrative examples are provided to demonstrate the theoretical analysis results.

关键词： Multi-agent systems     Controllability     Directed tree    

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Advances in the study of directed evolution for cellulases

Hailong LIN, Weiguang LI, Changhong GUO, Sihang QU, Nanqi REN

《环境科学与工程前沿（英文）》 2011年 第5卷 第4期   页码 519-525 doi: 10.1007/s11783-011-0326-2

摘要： If cellulose can be effectively hydrolyzed into glucose by cellulase, the production costs of hydrogen, ethanol or other chemicals from cellulosic materials will be greatly decreased, and economically viable production of biohydrogen and bioethanol will become feasible. Cellulose is degraded into glucoses by multi-component enzyme systems. Nowadays cellulases are widely used in brewing, food, bioenergy, fodder, textiles, paper, pharmaceuticals, environmental protection and other industries. However, existing cellulases have several problems that limit their wider applications, including the low turnover number for solid cellulosic materials, and low stability in adapting to various application conditions. For example, high temperature, low pH, and so on. Application of directed evolution technology may be one of the most effective ways for improving the characteristics of cellulases. This paper presents a brief review of the cellulose hydrolysis mechanism by cellulase, advances in cellulases (endoglucanase and -glucosidase) improvement by directed evolution for several characteristics (for instance, thermal stability, pH adaptability and enzyme activity), limitations of directed evolution for cellulases, and the outlook for directed evolution for cellulase.

关键词： biohydrogen     bioethanol     cellulase     cellulose     directed evolution    

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Kd-tree and quad-tree decompositions for declustering of 2D range queries over uncertain space

Ahmet SAYAR,Süleyman EKEN,Okan ÖZTÜRK

《信息与电子工程前沿（英文）》 2015年 第16卷 第2期   页码 98-108 doi: 10.1631/FITEE.1400165

摘要： We present a study to show the possibility of using two well-known space partitioning and indexing techniques, kd trees and quad trees, in declustering applications to increase input/output (I/O) parallelization and reduce spatial data processing times. This parallelization enables time-consuming computational geometry algorithms to be applied efficiently to big spatial data rendering and querying. The key challenge is how to balance the spatial processing load across a large number of worker nodes, given significant performance heterogeneity in nodes and processing skews in the workload.

关键词： Kd tree     Quad tree     Space partitioning     Spatial indexing     Range queries     Query optimization    

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Deep convolutional tree-inspired network: a decision-tree-structured neural network for hierarchical

《机械工程前沿（英文）》 2021年 第16卷 第4期   页码 814-828 doi: 10.1007/s11465-021-0650-6

摘要： The fault diagnosis of bearings is crucial in ensuring the reliability of rotating machinery. Deep neural networks have provided unprecedented opportunities to condition monitoring from a new perspective due to the powerful ability in learning fault-related knowledge. However, the inexplicability and low generalization ability of fault diagnosis models still bar them from the application. To address this issue, this paper explores a decision-tree-structured neural network, that is, the deep convolutional tree-inspired network (DCTN), for the hierarchical fault diagnosis of bearings. The proposed model effectively integrates the advantages of convolutional neural network (CNN) and decision tree methods by rebuilding the output decision layer of CNN according to the hierarchical structural characteristics of the decision tree, which is by no means a simple combination of the two models. The proposed DCTN model has unique advantages in 1) the hierarchical structure that can support more accuracy and comprehensive fault diagnosis, 2) the better interpretability of the model output with hierarchical decision making, and 3) more powerful generalization capabilities for the samples across fault severities. The multiclass fault diagnosis case and cross-severity fault diagnosis case are executed on a multicondition aeronautical bearing test rig. Experimental results can fully demonstrate the feasibility and superiority of the proposed method.

关键词： bearing     cross-severity fault diagnosis     hierarchical fault diagnosis     convolutional neural network     decision tree    

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Unnormalized and normalized forms of gefura measures in directed and undirected networks

Raf GUNS,Ronald ROUSSEAU

《信息与电子工程前沿（英文）》 2015年 第16卷 第4期   页码 311-320 doi: 10.1631/FITEE.1400425

摘要： In some networks nodes belong to predefined groups (e.g., authors belong to institutions). Common network centrality measures do not take this structure into account. Gefura measures are designed as indicators of a node’s brokerage role between such groups. They are defined as variants of betweenness centrality and consider to what extent a node belongs to shortest paths between nodes from different groups. In this article we make the following new contributions to their study: (1) We systematically study unnormalized gefura measures and show that, next to the ‘structural’ normalization that has hitherto been applied, a ‘basic’ normalization procedure is possible. While the former normalizes at the level of groups, the latter normalizes at the level of nodes. (2) Treating undirected networks as equivalent to symmetric directed networks, we expand the definition of gefura measures to the directed case. (3) It is shown how Brandes’ algorithm for betweenness centrality can be adjusted to cover these cases.

关键词： Networks subdivided in groups     Partitions     Gefura measures     Q-measures     Brokerage role     Directed and undirected networks     Brandes’     algorithm    

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Ionic strength directed self-assembled polyelectrolyte single-bilayer membrane for low-pressure nanofiltration

《化学科学与工程前沿（英文）》 2022年 第16卷 第5期   页码 699-708 doi: 10.1007/s11705-021-2093-3

摘要： Layer-by-layer assembly is a versatile technique for fabricating nanofiltration membranes, where multiple layers of polyelectrolytes are usually required to achieve reasonable separation performance. In this work, an ionic strength directed self-assembly procedure is described for the preparation of nanofiltration membranes consisting of only a single bilayer of poly(diallyldimethylammoniumchloride) and poly(sodium-4-styrenesulfoate). The influence of background ionic strength as well as membrane substrate properties on the formation of single-bilayer membranes are systematically evaluated. Such a simplified polyelectrolyte deposition procedure results in membranes having outstanding separation performance with permeating flux of 14.2 ± 1.5 L∙m–2∙h–1∙bar–1 and Na2SO4 rejection of 97.1% ± 0.8% under a low applied pressure of 1 bar. These results surpass the ones for conventional multilayered polyelectrolyte membranes. This work encompasses an investigation of ionic strength induced coiling of the polyelectrolyte chains and emphasizes the interplay between-polyelectrolyte chain configuration and substrate pore profile. It thus introduces a new concept on the control of membrane fabrication process toward high performance nanofiltration.

关键词： layer-by-layer self-assembly     single bilayer     nanofiltration membrane     desalination    

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中国油用牡丹工程的战略思考

李育材

《中国工程科学》 2014年 第16卷 第10期   页码 58-63

摘要：

作为一种原产于我国的多年生小灌木，油用牡丹具有抗性强、适应范围广、产量高和油质好等特点。大力发展油用牡丹对促进我国油料生产、保障粮油安全、改善生态环境、增加农民收入、帮助贫困地区农民脱贫致富等都具有十分重要的意义。本文介绍了发展油用牡丹的重要意义，并通过分析油用牡丹发展中现存的问题，提出了对我国油用牡丹工程发展的建议与思考。

关键词： 油用牡丹     木本油料     工程     战略思考    

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Water quality soft-sensor prediction in anaerobic process using deep neural network optimized by Tree-structured

《环境科学与工程前沿（英文）》 2023年 第17卷 第6期 doi: 10.1007/s11783-023-1667-3

摘要：

● Hybrid deep-learning model is proposed for water quality prediction.

关键词： Water quality prediction     Soft-sensor     Anaerobic process     Tree-structured Parzen Estimator    

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Liver-directed treatment is associated with improved survival and increased response to immune checkpoint

《医学前沿（英文）》   页码 878-888 doi: 10.1007/s11684-023-0993-y

摘要： Metastases of uveal melanoma (UM) spread predominantly to the liver. Due to low response rates to systemic therapies, liver-directed therapies (LDT) are commonly used for tumor control. The impact of LDT on the response to systemic treatment is unknown. A total of 182 patients with metastatic UM treated with immune checkpoint blockade (ICB) were included in this analysis. Patients were recruited from prospective skin cancer centers and the German national skin cancer registry (ADOReg) of the German Dermatologic Cooperative Oncology Group (DeCOG). Two cohorts were compared: patients with LDT (cohort A, n = 78) versus those without LDT (cohort B, n = 104). Data were analyzed for response to treatment, progression-free survival (PFS), and overall survival (OS). The median OS was significantly longer in cohort A than in cohort B (20.1 vs. 13.8 months; P = 0.0016) and a trend towards improved PFS was observed for cohort A (3.0 vs. 2.5 months; P = 0.054). The objective response rate to any ICB (16.7% vs. 3.8%, P = 0.0073) and combined ICB (14.1% vs. 4.5%, P = 0.017) was more favorable in cohort A. Our data suggest that the combination of LDT with ICB may be associated with a survival benefit and higher treatment response to ICB in patients with metastatic UM.

关键词： uveal melanoma     liver-directed therapy     immune checkpoint blockade     SIRT     anti-PD-1     anti-CTLA-4    

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Clinical outcomes of ATP-tumor chemosensitivity assay directed chemotherapy in hepatocellular carcinoma

RAO Rongsheng, CHEN Wenxue, ZHOU Xinwen, ZHOU Zheng, LI Xiaojun, ZENG Zhiping

《医学前沿（英文）》 2007年 第1卷 第2期   页码 157-160 doi: 10.1007/s11684-007-0029-z

摘要： This study aims to investigate the clinical response of ATP tumor chemosensitivity assay (ATP-TCA) directed chemotherapy regimens delivered via hepatic artery infusion in 104 cases of primary liver carcinoma (PLC). Tumor tissue was obtained via laparotomy and cultivated in vitro. This tissue was put through the assay to determine chemosensitivity. A single drug regimen of either 5-FU, MMC and ADM and a combination drug regimen were used. The treatment assigned was dependent on the result of the ATP-TCA. In the control group, 30 cases of diagnosed PLC were given the conventional three-combination drug. The two groups were evaluated after three courses of chemotherapy. The results are as follows. The overall response rate of sensitivity test ranged from 36% to 44% in the single drug therapy groups and 81% in the combination drug group. The clinical overall response rate was 75% in the treatment group and 56% in control group. The treatment group had better results than the control group as survival period over six months was 80% and over one year 44%. In the control group, survival period over six months was 60% and 30% over one year. In short, ATP-TCA directed chemotherapy shows better results for terminal stages of PLC in that you can decrease the dose of drugs thereby reducing the side-effects with possible improvements in therapeutic effects.
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Site-directed mutagenesis of long QT syndrome KCNQ1 gene

LI Wei, WANG Bin, XU Qiumei, KE Qinmei, YANG Junguo, DU Rong, TIAN Li, WANG Qing

《医学前沿（英文）》 2008年 第2卷 第1期   页码 100-104 doi: 10.1007/s11684-008-0018-x

摘要： To construct a polymerase chain reaction (PCR) site-directed mutagenesis of the long QT syndrome KCNQ1 gene , two sets of primers were designed according to the sequence of KCNQ1 cDNA and a mismatch was introduced into primers. Mutagenesis was performed in a two-step PCR. The amplified fragments from the third PCR which contained the mutation site were sub-cloned into the T-vector pCR2.1. Then, the fragments containing the mutation site was obtained from pCR2.1 using restriction enzymes digestion and inserted into the same restriction site of pIRES-EGFP-KCNQ1. The sequencing analysis shows that the mutation site was correct. Mutation from A to G in site 983 of KCNQ1 cDNA was found. Using the Effectene transfection reagent, pIRES-EGFP-KCNQ1 (G983A) was transfected into HEK cells successfully. These results may shed light on further functional study of KCNQ1 gene.

关键词： restriction     digestion     syndrome     sequence     site-directed mutagenesis    

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Heuristic solution using decision tree model for enhanced XML schema matching of bridge structural calculation

Sang I. PARK, Sang-Ho LEE

《结构与土木工程前沿（英文）》 2020年 第14卷 第6期   页码 1403-1417 doi: 10.1007/s11709-020-0666-8

摘要： Research on the quality of data in a structural calculation document (SCD) is lacking, although the SCD of a bridge is used as an essential reference during the entire lifecycle of the facility. XML Schema matching enables qualitative improvement of the stored data. This study aimed to enhance the applicability of XML Schema matching, which improves the speed and quality of information stored in bridge SCDs. First, the authors proposed a method of reducing the computing time for the schema matching of bridge SCDs. The computing speed of schema matching was increased by 13 to 1800 times by reducing the checking process of the correlations. Second, the authors developed a heuristic solution for selecting the optimal weight factors used in the matching process to maintain a high accuracy by introducing a decision tree. The decision tree model was built using the content elements stored in the SCD, design companies, bridge types, and weight factors as input variables, and the matching accuracy as the target variable. The inverse-calculation method was applied to extract the weight factors from the decision tree model for high-accuracy schema matching results.

关键词： structural calculation document     bridge structure     XML Schema matching     weight factor     data mining     decision tree model    

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An innovative model for predicting the displacement and rotation of column-tree moment connection under

Mohammad Ali NAGHSH, Aydin SHISHEGARAN, Behnam KARAMI, Timon RABCZUK, Arshia SHISHEGARAN, Hamed TAGHAVIZADEH, Mehdi MORADI

《结构与土木工程前沿（英文）》 2021年 第15卷 第1期   页码 194-212 doi: 10.1007/s11709-020-0688-2

摘要： In this study, we carried out nonlinear finite element simulations to predict the performance of a column-tree moment connection (CTMC) under fire and static loads. We also conducted a detailed parameter study based on five input variables, including the applied temperature, number of flange bolts, number of web bolts, length of the beam, and applied static loads. The first variable is changed among seven levels, whereas the other variables are changed among three levels. Employing the Taguchi method for variables 2–5 and their levels, 9 samples were designed for the parameter study, where each sample was exposed to 7 different temperatures yielding 63 outputs. The related variables for each output are imported for the training and testing of different surrogate models. These surrogate models include a multiple linear regression (MLR), multiple Ln equation regression (MLnER), an adaptive network-based fuzzy inference system (ANFIS), and gene expression programming (GEP). 44 samples were used for training randomly while the remaining samples were employed for testing. We show that GEP outperforms MLR, MLnER, and ANFIS. The results indicate that the rotation and deflection of the CTMC depend on the temperature. In addition, the fire resistance increases with a decrease in the beam length; thus, a shorter beam can increase the fire resistance of the building. The numbers of flanges and web bolts slightly affect the rotation and displacement of the CTMCs at temperatures of above 400°C.

关键词： column-tree moment connection     Finite element model     parametric study     fire     regression models     gene expression programming    

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oocyst directed assembly of gold nanoparticles and graphene oxide

Sona Jain, Zhicheng Huang, Brent R. Dixon, Syed Sattar, Juewen Liu

《化学科学与工程前沿（英文）》 2019年 第13卷 第3期   页码 608-615 doi: 10.1007/s11705-019-1813-4

摘要： Understanding the interactions between inorganic nanomaterials and biological species is an important topic for surface and environmental chemistry. In this work, we systematically studied the oocysts of as a model protozoan parasite and its interaction with gold nanoparticles (AuNPs) and graphene oxide (GO). The as-prepared citrate-capped AuNPs adsorb strongly on the oocysts leading to a vivid color change. The adsorption of the AuNPs was confirmed by transmission electron microscopy. Heat treatment fully inhibited the color change, indicating a large change of surface chemistry of the oocysts that can be probed by the AuNPs. Adding proteases such as trypsin and proteinase K partially inhibited the color change. DNA-capped AuNPs, on the other hand, could not be adsorbed by the oocysts. GO was found to wrap around the oocysts forming a conformal shell reflecting the shape of the oocysts. Both citrate-capped AuNPs and GO compromised the membrane integrity of the oocysts as indicated by the propidium iodide staining experiment, and they may be potentially used for inactivating the oocysts. This is the first example of using nanomaterials to probe the surface of the oocysts, and it suggests the possibility of using such organisms to template the assembly of nanomaterials.

关键词： nanomaterials     toxicology     water     biosensors    

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Salt-assisted synthesis of tree-like oriented SnO

Jinquan SUN, Zifeng YAN, Hongzhi CUI

《化学科学与工程前沿（英文）》 2011年 第5卷 第2期   页码 227-230 doi: 10.1007/s11705-010-0566-x

摘要： Tree-like SnO nanodendrites in large amounts have been prepared through two-step reactions. The nanoparticles used as the precursors have taken aggregation forming tree-like or string of nanodendrtie. The samples were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), high-resolution transmission electron microscopy (HRTEM) and energy dispersive spectrometer (EDS), respectively. The results showed that molar ratio of the ethanol/distilled water is an important factor for formation of the different dendrite structures. There are different morphologies between tree-like SnO nanowhiskers and bunch of SnO nanorods. However, they are growing along the .

关键词： crystal morphology     nano-structures     nanodendrite    

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标题 作者 时间 类型 操作

Controllability analysis of second-ordermulti-agent systemswith directed andweighted interconnection

Di GUO,Rong-hao ZHENG,Zhi-yun LIN,Gang-feng YAN

期刊论文

Advances in the study of directed evolution for cellulases

Hailong LIN, Weiguang LI, Changhong GUO, Sihang QU, Nanqi REN

期刊论文

Kd-tree and quad-tree decompositions for declustering of 2D range queries over uncertain space

Ahmet SAYAR,Süleyman EKEN,Okan ÖZTÜRK

期刊论文

Deep convolutional tree-inspired network: a decision-tree-structured neural network for hierarchical

期刊论文

Unnormalized and normalized forms of gefura measures in directed and undirected networks

Raf GUNS,Ronald ROUSSEAU

期刊论文

Ionic strength directed self-assembled polyelectrolyte single-bilayer membrane for low-pressure nanofiltration

期刊论文

中国油用牡丹工程的战略思考

李育材

期刊论文

Water quality soft-sensor prediction in anaerobic process using deep neural network optimized by Tree-structured

期刊论文

Liver-directed treatment is associated with improved survival and increased response to immune checkpoint

期刊论文

Clinical outcomes of ATP-tumor chemosensitivity assay directed chemotherapy in hepatocellular carcinoma

RAO Rongsheng, CHEN Wenxue, ZHOU Xinwen, ZHOU Zheng, LI Xiaojun, ZENG Zhiping

期刊论文

Site-directed mutagenesis of long QT syndrome KCNQ1 gene

LI Wei, WANG Bin, XU Qiumei, KE Qinmei, YANG Junguo, DU Rong, TIAN Li, WANG Qing

期刊论文

Heuristic solution using decision tree model for enhanced XML schema matching of bridge structural calculation

Sang I. PARK, Sang-Ho LEE

期刊论文

An innovative model for predicting the displacement and rotation of column-tree moment connection under

Mohammad Ali NAGHSH, Aydin SHISHEGARAN, Behnam KARAMI, Timon RABCZUK, Arshia SHISHEGARAN, Hamed TAGHAVIZADEH, Mehdi MORADI

期刊论文

oocyst directed assembly of gold nanoparticles and graphene oxide

Sona Jain, Zhicheng Huang, Brent R. Dixon, Syed Sattar, Juewen Liu

期刊论文

Salt-assisted synthesis of tree-like oriented SnO

Jinquan SUN, Zifeng YAN, Hongzhi CUI

期刊论文